You are here

    Circulating Tumour Cell (CTC) Analysis

    NIIM is pleased to offer CTC analysis service, using the ISET (Rarecells, France) system, in our NIIM laboratory.

    What is Circulating Tumour Cell (CTC) analysis?

    • CTC’s are Circulating Tumour Cells in the blood
    • The number of CTC cells indicates the stage of cancer in a person
    • CTC Analysis counts the number of CTC cells
    • CTC may help measure the effectiveness of cancer treatments
    • NIIM’s CTC Analysis method is well established overseas and validated by substantial research
    • NIIM conducts the ISET®-CTC test as part of a clinical study. This study has been approved by an NHMRC registered ethics committee, and is registered on the Australian New Zealand Clinical Trials Registry.

    To make a booking for the CTC Test, please contact the NIIM Clinic at (03) 9804 0646

    For more information contact the NIIM Research Director Dr Karin Ried on:
    P (03) 9912 9545 E karinried@niim.com.au

     

    CTC Test Request Forms

    Please be aware there are seperate Victorian and Interstate request forms, Interstate request forms include an additional express shipping and handling cost.

    Victoria Patients Form - Download Victorian CTC Test request form here

    Interstate Patients Form - Download Interstate (Non-Victorian) CTC Test request form here

    From 1st of June 2016 the cost of the CTC test at NIIM is $850.
    Please note there's an additional shipping fee of $100 for interstate kits.

     

     

     

    Some FACTS about the ISET-CTC Test:

    1. FACT 1: The ISET-CTC tests can detect Circulating Tumour Cells (CTC) in all cancer types, including solid tumours and blood type cancers.
    2. FACT 2: The ISET-CTC test can detect small cell cancer cells. ISET-CTC (Isolation of Epithelial Tumour Cells by Size) testing by microfiltration can detect cancer cells of all sizes. Cancer cells usually are larger than 8 microns (the ISET filter hole size), including solid tumour cells of 11.7-23.8 microns, small-cell type cancers (e.g. small cell lung carcinoma of 7.2-10 microns) and blood type cancers (e.g. leukemia cells of 8.9-15.3 microns).​​
    3. FACT 3: The ISET-CTC can detect Circulating Tumour Cells (CTC) independent of the presence of Epithelial Cell Adhesion Molecule (EpCAM) markers.
      - Some tumour cells do not have EpCAM markers, e.g. blood type tumours.
      - Tumour cells consistently undergo change and may lose EpCAM markers over time.
    4. FACT 4: The ISET-CTC testing can distinguish between malignant Circulating Tumour Cells (CTC) and benign Circulating Epithelial Cells (CEC).

    References: Paterlini–Brechot P. Circulating Tumour Cells: Who is the Killer? Cancer Microenviron 2014;7,161-176.; Vona G et al. Isolation by size of epithelial tumor cells : a new method for the immunomorphological and molecular characterization of circulatingtumor cells. Am J Pathol 2000;156(1):57-63. Harouaka RA et al. Circulating Tumour Cell enrichment based on physical properties. J Lab Autom 2013;18(6),1-21.

     

    Download the NIIM CTC Brochure